Article
Screening with the activated protein C resistance assay yields significant savings in a patient population with low prevalence of factor V leiden.
American journal of clinical pathology - 1 Mar 2008
Taylor Laura J, Oster Robert A, Fritsma George A, Tichenor Patricia H, Reed Cari E, Eiland Barbara M, Hudson Christine L, Marques Marisa B
Abstract excerpt
Testing for factor V Leiden can be performed with a molecular assay or a test for activated protein C resistance. We noted that physicians in our institution tended to order the molecular test 80% of the time, but the prevalence of the mutation in our patient population was less than 10%. Consequently, we decided to introduce the activated protein C resistance assay in house and consistently use it for screening...
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