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Article

Successful adjuvant-free vaccination of BALB/c mice with mutated amyloid beta peptides.

BMC neuroscience - 18 Feb 2008

Cao Chuanhai, Lin Xiaoyang, Wahi Monika M, Jackson Eugene A, Potter Huntington

Abstract excerpt

BACKGROUND: A recent human clinical trial of an Alzheimer's disease (AD) vaccine using amyloid beta (Abeta) 1-42 plus QS-21 adjuvant produced some positive results, but was halted due to meningoencephalitis in some participants. The development of a vaccine with mutant Abeta peptides that avoids...

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Identifiers

PMID: 18282292
DOI: 10.1186/1471-2202-9-25
PMCID: PMC2270279

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18282292-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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