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Article

Mutant amyloid-beta-sensitized dendritic cells as Alzheimer's disease vaccine.

Journal of neuroimmunology - 30 Aug 2008

Cao Chuanhai, Lin Xiaoyang, Zhang Chi, Wahi Monika M, Wefes Inge, Arendash Gary, Potter Huntington

Abstract excerpt

Vaccines using bone marrow-derived dendritic cells (DCs) sensitized to Abeta 1-42 peptide and other mutant peptides were tested on BALB/c and APP(SW) transgenic mice. Wild type Abeta 1-42-sensitized DC vaccine (DCSV) produced no response, but all peptides with a T-cell epitope mutation induced antibody responses without inflammation. DCSV with Abeta 1-25 peptide with mutated T-cell epitope failed to induce...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18649951
DOI: 10.1016/j.jneuroim.2008.05.017

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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