SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae.

doi:10.1016/0092-8674(91)90386-d

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Article

SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae.

Cell - 31 May 1991

Irie K, Nomoto S, Miyajima I, Matsumoto K

Abstract excerpt

The GPA1 gene of S. cerevisiae encodes a G alpha subunit that plays a positive role in the transduction of signals stimulating recovery from pheromone-induced cell cycle arrest. The GPA1Val50 mutation, in which Gly-50 is replaced by valine, causes hyperadaptation to pheromone. However, GPA1Val50 cells do not recover from division arrest in the absence of both CLN1 and CLN3, which encode G1 cyclins, indicating...

Topics

Amino Acid Sequence
Base Sequence
CDC2 Protein Kinase
CDC2-CDC28 Kinases
Cloning, Molecular
Cyclins
GTP-Binding Proteins
Genes, Fungal
Genotype
Mating Factor
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Peptides

Phenotype

Pheromones

Protein Kinases

Saccharomyces cerevisiae

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 1828190
DOI: 10.1016/0092-8674(91)90386-d

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1828190-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae.PMID 1828190Read ↗

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Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors.Semantic proximity Read ↗

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