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Article

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

Biochemical and biophysical research communications - 8 Jun 2001

Cismowski M J, Metodiev M, Draper E, Stone D E

Abstract excerpt

The mating-specific heterotrimeric G(alpha) protein of Saccharomyces cerevisiae, Gpa1, negatively regulates activation of the pheromone response pathway both by sequestering G(beta)gamma and by triggering an adaptive response through an as yet unknown mechanism. Previous genetic studies identified mutant alleles of GPA1 that downregulate the pheromone response independently of the pheromone receptor (GPA1E364K),...

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PMID: 11394869
DOI: 10.1006/bbrc.2001.4959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.PMID 11394869Read ↗

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