Article
Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway.
Molecular and cellular biology - 1 Jun 1990
Kang Y S, Kane J, Kurjan J, Stadel J M, Tipper D J
Abstract excerpt
Scg1, the product of the Saccharomyces cerevisiae SCG1 (also called GPA1) gene, is homologous to the alpha subunits of G proteins involved in signal transduction in mammalian cells. Scg1 negatively controls the pheromone response pathway in haploid cells. Either pheromonal activation or an scg1 n...
Topics
- Animals
- Base Sequence
- Crosses, Genetic
- GTP-Binding Proteins
- Gene Expression
- Genetic Complementation Test
- Genetic Vectors
- Macromolecular Substances
- Mating Factor
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Peptides
- Pheromones
- Plasmids
- Protein Multimerization
- Rats