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Article

UEV-1 is an ubiquitin-conjugating enzyme variant that regulates glutamate receptor trafficking in C. elegans neurons.

PloS one - 13 Dec 2010

Kramer Lawrence B, Shim Jaegal, Previtera Michelle L, Isack Nora R, Lee Ming-Chih, Firestein Bonnie L, Rongo Christopher

Abstract excerpt

The regulation of AMPA-type glutamate receptor (AMPAR) membrane trafficking is a key mechanism by which neurons regulate synaptic strength and plasticity. AMPAR trafficking is modulated through a combination of receptor phosphorylation, ubiquitination, endocytosis, and recycling, yet the factors that mediate these processes are just beginning to be uncovered. Here we identify the ubiquitin-conjugating enzyme...

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Identifiers

PMID: 21179194
DOI: 10.1371/journal.pone.0014291
PMCID: PMC3001443

Genes

UBC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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