Article
Sequence-specific DNA binding by Myc proteins.
Proceedings of the National Academy of Sciences of the United States of America - 15 May 1991
Kerkhoff E, Bister K, Klempnauer K H
Abstract excerpt
Myc proteins have a tripartite carboxyl-terminal domain containing specific amino acid sequence motifs: a basic motif, a helix-loop-helix motif, and a leucine heptad repeat. Similar sequence motifs have been identified in several eukaryotic transcription factors and were shown to facilitate protein-DNA and protein-protein interactions. By using recombinant v-Myc proteins obtained by bacterial expression of...
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