Article
Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC.
International journal of oncology - 1 Dec 2008
Teye Kwesi, Okamoto Kengo, Tanaka Yuji, Umata Toshiyuki, Ohnuma Masaaki, Moroi Masaaki, Kimura Hiroshi, Tsuneoka Makoto
Abstract excerpt
Transcription factor binding sites are short DNA sequences that interact with transcription factors and the proper control of gene expression appears to require the mechanisms including the regulation through the genome context around the transcription factor binding sites. The MYC proteins are central regulators of cell growth. Many genes have been reported to be regulated by MYC through E-box sites. However,...
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