Article
PAI-1 haplogenotype confers genetic susceptibility for obesity and hypertriglyceridemia in Mexican children.
Investigacion clinica - 1 Sept 2016
de la Cruz-Mosso Ulises, Elena Ramos-Arellano Luz, Francisco Muñoz-Valle José, Berenice Salgado-Bernabé Aralia, Salgado-Goytia Lorenzo, Castro-Alarcón Natividad, Ramírez-Peralta Arturo, Parra-Rojas Isela
Abstract excerpt
The presence of childhood obesity predisposes to the development of cardiovascular and metabolic diseases, such as coronary artery disease and type 2 diabetes mellitus, in adulthood. The polymorphisms described in PAI-1 gene have been linked with obesity and metabolic syndrome in several populations. The aim of this study was to investigate the association of the -844 G/A (rs2227631), -675 4G/5G (rs1799889) and...
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