Article
Association of leprosy with HLA-DRB1 in an Argentinean population.
Annals of clinical biochemistry - 1 Jan 2008
Borrás Silvia García, Cotorruelo Carlos, Racca Liliana, Recarte Mónica, Garcías Celeste, Biondi Claudia, Bottasso Oscar, Racca Amelia
Abstract excerpt
BACKGROUND: Previous studies have suggested an influence of HLA molecules on the regulation of the anti Mycobacterium leprae immune response. METHODS: DNA typing of HLA-DRB1 alleles in 71 leprosy patients and 81 healthy controls was performed. Genomic DNA was extracted from peripheral blood and used as a template to amplify the polymorphic second exon of the HLA-DRB1 by the polymerase chain reaction (PCR). PCR...
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