Article
Human leukocyte antigen class I and class II alleles are associated with susceptibility and resistance in borderline leprosy patients from Southeast Brazil.
BMC infectious diseases - 21 Jan 2015
de Souza-Santana Fabiana Covolo, Marcos Elaine Valim Camarinha, Nogueira Maria Esther Salles, Ura Somei, Tomimori Jane
Abstract excerpt
BACKGROUND: Evidence suggests that human leukocyte antigen (HLA) alleles influence the host immune response against Mycobacterium leprae. However, the association between HLA alleles and borderline (B) leprosy has not been studied. The aim of this study was to determine whether HLA class I and II molecules are associated with susceptibility or resistance to B leprosy including borderline-tuberculoid (BT),...
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