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Article

Leukemia in Down syndrome: a review.

Pediatric hematology and oncology - 1 Jan 2000

Zipursky A, Poon A, Doyle J

Abstract excerpt

The incidence of leukemia is higher in children with Down syndrome (DS) than in normals. In approximately 50% of cases the type of leukemia is acute megakaryoblastic leukemia (AMKL) and it occurs during the first 4 years of life. The leukemic cell also has features of erythroid progenitors and therefore appears to be a precursor cell with biphenotypic properties. In addition, newborns with DS frequently develop...

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Identifiers

PMID: 1388043
DOI: 10.3109/08880019209018329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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