Article
Long-term white noise exposure-induced mtDNA deletion in the auditory system.
Acta oto-laryngologica - 1 Mar 2008
Han Weiju, Shi Yongbing, Yang Weiyan, Han Dongyi
Abstract excerpt
CONCLUSION: Long-term exposure to broadband noise can lead to increased levels of mtDNA4834 deletion in the auditory system in rats. OBJECTIVE: This study aimed to determine if long-term noise exposure induces mtDNA deletion in the auditory system. MATERIALS AND METHODS: Wistar rats aged 3 months (n =20) were exposed to 110 dB SPL white noise, 4 h per day, for 20 consecutive days. The control group included...
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