Article
The relation between D-galactose injection and mitochondrial DNA 4834 bp deletion mutation.
Experimental gerontology - 1 Jun 2006
Kong Wei-jia, Wang Ying, Wang Qiong, Hu Yu-juan, Han Yue-chen, Liu Jun
Abstract excerpt
Since,D-galactose (D-gal) overload model has been used as a premature aging model, we hypothesized that it may also lead to accelerated aging in the inner ear. Furthermore, though the mitochondrial DNA (mtDNA) 4834 bp deletion mutation has been considered as the marker of aging, there is no information available in the literature concerning the mtDNA 4834 bp deletion mutation condition of the D-gal induced...
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