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Polymorphisms in the FAS gene are associated with susceptibility to noise-induced hearing loss.

Environmental science and pollution research international - 1 May 2021

Xu Shouxiang, Wang Boshen, Han Lei, Pu Yuepu, Zhu Baoli, Zhang Juan

Abstract excerpt

This study investigated the relationship between genetic polymorphisms in the FAS gene and noise-induced hearing loss (NIHL) risk among Chinese workers exposed to occupational noise, and the molecular mechanism of NIHL caused by noise. In this case-control study, 692 NIHL workers and 650 controls were selected for genotyping of four single nucleotide polymorphisms (SNPs) of the FAS gene. Logistic regression was...

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PMID: 33411277
DOI: 10.1007/s11356-020-12028-9

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