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Article

Docking and multivariate methods to explore HIV-1 drug-resistance: a comparative analysis.

Journal of computer-aided molecular design - 1 May 2008

Almerico Anna Maria, Tutone Marco, Lauria Antonino

Abstract excerpt

In this paper we describe a comparative analysis between multivariate and docking methods in the study of the drug resistance to the reverse transcriptase and the protease inhibitors. In our early papers we developed a simple but efficient method to evaluate the features of compounds that are less likely to trigger resistance or are effective against mutant HIV strains, using the multivariate statistical...

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Identifiers

PMID: 18273557
DOI: 10.1007/s10822-008-9186-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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