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Article

Visualization of Protein-Drug Interactions for the Analysis of Drug Resistance in Lung Cancer.

IEEE journal of biomedical and health informatics - 1 May 2021

Qureshi Rizwan, Zhu Mengxu, Yan Hong

Abstract excerpt

Non-small cell lung cancer (NSCLC) caused by mutation of the epidermal growth factor receptor (EGFR) is a major cause of death worldwide. Tyrosine kinase inhibitors (TKIs) of EGFR have been developed and show promising results at the initial stage of therapy. However, in most cases, their efficacy becomes limited due to the emergence of secondary mutations causing drug resistance after about a year. In this work,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32991295
DOI: 10.1109/JBHI.2020.3027511

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