Article
Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis.
Neurology - 25 Mar 2008
De Jager P L, Simon K C, Munger K L, Rioux J D, Hafler D A, Ascherio A
Abstract excerpt
BACKGROUND: Individuals with high levels of antibodies to the Epstein-Barr virus nuclear antigen 1 (EBNA-1) have an increased risk of developing multiple sclerosis (MS), but this association could be confounded by genetic susceptibility. METHODS: We conducted a nested case-control study including 148 women with MS (18 with blood collected before disease onset) and 296 age-matched healthy women to determine...
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