Article
Atbf1 is required for the Pit1 gene early activation.
Proceedings of the National Academy of Sciences of the United States of America - 19 Feb 2008
Qi Yingchuan, Ranish Jeffrey A, Zhu Xiaoyan, Krones Anna, Zhang Jie, Aebersold Ruedi, Rose David W, Rosenfeld Michael G, Carrière Catherine
Abstract excerpt
Enhancers have been functionally described for >35 years, but the molecular principles underlying the integration of regulatory inputs to alternate gene enhancers used during mammalian organogenesis remain incompletely understood. Using a combination of in vivo enhancer mapping and proteomics approaches, we have established that two distant and distinct early enhancers, each requiring different transcription...
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