Article

Identification of pituitary thyrotrope signature genes and regulatory elements

2020-08-06

Abstract excerpt

Pituitary thyrotropes are specialized cells that produce thyroid stimulating hormone (TSH), a critical factor for growth and maintenance of metabolism. The transcription factors POU1F1 and GATA2 have been implicated in thyrotrope fate and transcriptional regulation of the beta subunit of TSH, Tshb , but no transcriptomic or epigenomic analyses of these cells has been undertaken. The goal of this work was to disco...

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Literature Corpus work: cd229026-bc3c-5a5d-b87b-46a0baa37e02
DOI: 10.1101/2020.08.05.238253

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