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Article

Quantitative chiral analysis of salsolinol in different brain regions of rats genetically predisposed to alcoholism.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 1 Mar 2008

Rojkovicova Tatiana, Mechref Yehia, Starkey Jason A, Wu Guangxiang, Bell Richard L, McBride William J, Novotny Milos V

Abstract excerpt

A method to determine the catecholamine content in putamen (CPU) and midbrain (MB) regions of the brain of alcohol-preferring rats (P) is presented with a focus on the low-level detection of S,R-salsolinol, a metabolite of dopamine and a putative alcoholism marker. The developed strategy allows both quantitative profiling of related catecholamines and the enantiomeric separation and quantification of the S- and...

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PMID: 18272438
DOI: 10.1016/j.jchromb.2008.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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