Article
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2004
Pizarro Nieves, Farré Magí, Pujadas Mitona, Peiró Ana Ma, Roset Pere N, Joglar Jesús, de la Torre Rafael
Abstract excerpt
3,4-Methylenedioxymethamphetamine (MDMA; "ecstasy") is a designer drug commonly misused in large segments of young populations. MDMA is usually formulated in tablets of its racemate (1:1 mixture of its enantiomers) in doses ranging from 50 to 200 mg. MDMA has an enantioselective metabolism, the (S)-enantiomer being metabolized faster than the (R)-enantiomer. Different pharmacologic properties have been attributed...
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