Article
Pharmacological studies of alcohol susceptibility and brain monoamine function in stroke-prone spontaneously hypertensive rats (SHRSP) and stroke-resistant spontaneously hypertensive rats (SHRSR).
The Tohoku journal of experimental medicine - 1 Sept 2003
Yoshimoto Kanji, Komura Setsuo, Hattori Hiroyuki, Yamori Yukio, Miura Ayako, Yoshida Toshihide, Hioki Chizuko, Kato Baku, Fukuda Fuimihiko, Tanaka Shiho, Hirai Ayako, Nishimura Akira, Sawai Yasuko, Yasuhara Masahiro
Abstract excerpt
Differences of alcohol drinking behavior, brain dopamine (DA) and serotonin (5-HT) levels and releases in the striatum were investigated in stroke-prone spontaneously hypertensive rats (SHRSP) and age-matched stroke-resistant spontaneously hypertensive rats (SHRSR). Voluntary alcohol (EtOH) consumption in SHRSP rats increased at 1 and 2 hours in the 4 hour time access. In the DA level, SHRSP showed decreases in...
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