Article
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.
The Journal of experimental medicine - 1 May 1991
Hardy R R, Carmack C E, Shinton S A, Kemp J D, Hayakawa K
Abstract excerpt
We have resolved B220+ IgM- B-lineage cells in mouse bone marrow into four fractions based on differential cell surface expression of determinants recognized by S7 (leukosialin, CD43), BP-1, and 30F1 (heat stable antigen). Functional differences among these fractions can be correlated with Ig gene rearrangement status. The largest fraction, lacking S7, consists of pre-B cells whereas the others, expressing S7,...
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