Article
A phenotypically distinct subset of immature B cells exhibits partial activation, increased survival, and preferential expression of VhS107.
European journal of immunology - 1 Dec 2003
Wilson Emily L, Sherwood Erin M, King Anne M, Riley Richard L
Abstract excerpt
We have observed that immature B cells (IgM(low)IgD(-)) in the bone marrow of adult BALB/c mice exhibit heterogeneity, with a distinct subpopulation ( approximately 4-10%) expressing the CD43/S7 surface protein. These CD43/S7(+) immature B cells often express other surface antigens associated with B cell activation (CD5, CD11b, PD-1). Generation of optimal numbers of CD43/S7(+) immature B cells requires...
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