Article
Identification of the earliest B lineage stage in mouse bone marrow.
Immunity - 1 Dec 1996
Li Y S, Wasserman R, Hayakawa K, Hardy R R
Abstract excerpt
We have identified a very early stage of B lineage cells in the CD45R (B220)+CD24 (HSA) pre-pro-B fraction of mouse bone marrow delineated by expression of AA4.1, a molecule found on stem cells and early B lineage cells. These cells are B lineage precursors based on their capacity to generate B l...
Topics
- Animals
- Antigens, Differentiation
- B-Lymphocyte Subsets
- B-Lymphocytes
- Bone Marrow
- Bone Marrow Cells
- Cell Differentiation
- Cell Fractionation
- Cell Lineage
- DNA-Binding Proteins
- Female
- Gene Expression
- Hematopoietic Stem Cells
- Homeodomain Proteins
- Immunoglobulin Isotypes
- Mice
- Mice, Inbred BALB C
- Phenotype