Article
DISC1 mRNA expression is not influenced by common Cis-acting regulatory polymorphisms or imprinting.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Hayesmoore J B G, Bray N J, Owen M J, O'Donovan M C
Abstract excerpt
The hypothesis that genetic variation in Disrupted in Schizophrenia 1 (DISC1) influences risk of schizophrenia and other major psychiatric disorders is supported by a growing body of genetic association data and plausible functional biology. Risk of psychiatric disorder is not attributable to non-synonymous changes that alter the protein coding sequence of DISC1, although certain such variants possibly contribute...
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