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Article

mtDNA nt13708A variant increases the risk of multiple sclerosis.

PloS one - 13 Feb 2008

Yu Xinhua, Koczan Dirk, Sulonen Anna-Maija, Akkad Denis A, Kroner Antje, Comabella Manuel, Costa Gianna, Corongiu Daniela, Goertsches Robert, Camina-Tato Montserrat, Thiesen Hans-Juergen, Nyland Harald I, Mørk Sverre J, Montalban Xavier, Rieckmann Peter, Marrosu Maria G, Myhr Kjell-Morten, Epplen Joerg T, Saarela Janna, Ibrahim Saleh M

Abstract excerpt

BACKGROUND: Mitochondrial DNA (mtDNA) polymorphism is a possible factor contributing to the maternal parent-of-origin effect in multiple sclerosis (MS) susceptibility. METHODS AND FINDINGS: In order to investigate the role of mtDNA variations in MS, we investigated six European MS case-control cohorts comprising >5,000 individuals. Three well matched cohorts were genotyped with seven common, potentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18270557
DOI: 10.1371/journal.pone.0001530
PMCID: PMC2217590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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