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T16189C mitochondrial DNA variant is associated with metabolic syndrome in Caucasian subjects.

Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000

Palmieri Vincenzo Ostilio, De Rasmo Domenico, Signorile Anna, Sardanelli Anna Maria, Grattagliano Ignazio, Minerva Francesco, Cardinale Giovanna, Portincasa Piero, Papa Sergio, Palasciano Giuseppe

Abstract excerpt

OBJECTIVES: Different nuclear genes are thought to be involved in the regulation of the complex phenotype of metabolic syndrome (MS) and their number is increasing. A mutation in mitochondrial DNA (mtDNA), T4291C in transfer RNA isoleucine (tRNAile), has been associated with MS in a large American family. In addition, a mtDNA T16189C variant, already known to be associated with insulin resistance and type 2...

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Identifiers

PMID: 21146361
DOI: 10.1016/j.nut.2010.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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