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Article

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.

Blood - 15 Apr 2008

Salomon Ophira, Steinberg David M, Koren-Morag Nira, Tanne David, Seligsohn Uri

Abstract excerpt

Inherited disorders of hemostasis are natural models for investigating mechanisms of thrombosis and development of antithrombotic therapy. Because mice with total factor XI deficiency are protected against ischemic stroke and do not manifest excessive bleeding, we investigated the incidence of ischemic stroke in patients with severe inherited factor XI deficiency. Incidence of ischemic stroke in 115 patients aged...

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Identifiers

PMID: 18268095
DOI: 10.1182/blood-2007-10-120139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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