Article
Inherited factor XI deficiency confers no protection against acute myocardial infarction.
Journal of thrombosis and haemostasis : JTH - 1 Apr 2003
Salomon O, Steinberg D M, Dardik R, Rosenberg N, Zivelin A, Tamarin I, Ravid B, Berliner S, Seligsohn U
Abstract excerpt
BACKGROUND AND PURPOSE: Factor XI (FXI) contributes to thrombin generation thereby affecting fibrin formation and to down regulation of fibrinolysis by activation of thrombin-activatable fibrinolysis inhibitor (TAFI). The purpose of this study was to evaluate whether patients with severe FXI deficiency are protected against acute myocardial infarction (AMI). METHODS: The incidence of AMI in patients with severe...
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