Unraveling the role of defective genes in Parkinson's disease.

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons leading to bradykinesia, rest tremor and rigidity. Although the majority of PD is sporadic, rare genetic causes of PD are providing tremendous insight into the pathogenesis of PD. Here I shortly review the major genes implicated in autosomal dominant and autosomal recessive PD. Understanding how...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genes, Dominant
• Share to Genes, Recessive
• Share to Genetic Predisposition to Disease