Article
Recessive Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2006
Kubo Shin-ichiro, Hattori Nobutaka, Mizuno Yoshikuni
Abstract excerpt
Parkinson's disease (PD) is a progressive neurodegenerative disease caused by loss of dopaminergic neurons in the substantia nigra pars compacta. Although the etiology of PD remains unclear, it is now clear that genetic factors contribute to the pathogenesis of the disease. Recently, several causative genes have been identified in monogenic forms of PD. Accumulating evidence indicates that their gene products...
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