Article
Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process.
Cellular and molecular neurobiology - 1 Aug 2018
Karimi-Moghadam Amin, Charsouei Saeid, Bell Benjamin, Jabalameli Mohammad Reza
Abstract excerpt
Parkinson disease (PD) is known as a common progressive neurodegenerative disease which is clinically diagnosed by the manifestation of numerous motor and nonmotor symptoms. PD is a genetically heterogeneous disorder with both familial and sporadic forms. To date, researches in the field of Parkinsonism have identified 23 genes or loci linked to rare monogenic familial forms of PD with Mendelian inheritance....
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