Article
Comparison of properties of tests for assessing tumor clonality.
Biometrics - 1 Dec 2008
Ostrovnaya Irina, Seshan Venkatraman E, Begg Colin B
Abstract excerpt
SUMMARY: In a recent article Begg et al. (2007, Biometrics 63, 522-530) proposed a statistical test to determine whether or not a diagnosed second primary tumor is biologically independent of the original primary tumor, by comparing patterns of allelic losses at candidate genetic loci. The proposed concordant mutations test is a conditional test, an adaptation of Fisher's exact test, that requires no knowledge of...
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