Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene targeting in mouse embryos mediated by RecA and modified single-stranded oligonucleotides.

In vitro cellular & developmental biology. Animal - 1 Jan 2000

Kang Jee Hyun, Ahn Kwang Sung, Heo Soon Young, Won Ji Young, Shim Hosup

Abstract excerpt

Gene targeting is a precise manipulation of endogenous gene by introduction of exogenous DNA and has contributed greatly to the elucidation of gene functions. Conventional gene targeting has been achieved through a use of embryonic stem cells. However, such procedure is often long, tedious, and expensive. This study was carried out to develop a simple procedure of gene targeting using E. coli recombinase A (RecA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Single-Stranded

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Gene Targeting

Share to Oligonucleotides

Share to Rec A Recombinases

Share to Recombination, Genetic

Source

Identifiers

PMID: 18266050
DOI: 10.1007/s11626-007-9080-y

Genes

TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene targeting in mouse embryos mediated by RecA and modified single-stranded oligonucleotides.PMID 18266050Read ↗

Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells.Semantic proximity Read ↗

Oligonucleotide-directed mutagenesis and targeted gene correction: a mechanistic point of view.Semantic proximity Read ↗

Overview of gene targeting by homologous recombination.Semantic proximity Read ↗

Use of two gRNAs for CRISPR/Cas9 improves bi-allelic homologous recombination efficiency in mouse embryonic stem cells.Semantic proximity Read ↗

Genetic manipulation of mouse embryonic stem cells by mutant lambda integrase.Semantic proximity Read ↗

Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs.Semantic proximity Read ↗

Efficient Gene Targeting Mediated by Adeno-Associated Virus and DNA Double-Strand BreaksSemantic proximity Read ↗

Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactions.Semantic proximity Read ↗

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.Semantic proximity Read ↗

Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents.Semantic proximity Read ↗

Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells.Semantic proximity Read ↗

Targeted gene modification in mismatch-repair-deficient embryonic stem cells by single-stranded DNA oligonucleotides.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.