Article
Drosophila female sterile (1) homeotic is a multifunctional transcriptional regulator that is modulated by Ras signaling.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2008
Florence Brian L, Faller Douglas V
Abstract excerpt
The Drosophila (fs(1)h) gene encodes small (Fs(1)hS) and large (Fs(1)hL) chromatin-binding BET protein transcription factor isoforms. Zygotic mutations cause either lethality or female sterility, whereas maternal mutations cause segmental deletions and thoracic homeotic transformations. Here, we describe novel fs(1)h embryonic phenotypes: homeosis of the head in zygotic mutants and deletion of head and tail...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Developmental
- Genes, Insect