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Article

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.

Development (Cambridge, England) - 1 Jun 2005

Nishioka Noriyuki, Nagano Seiichi, Nakayama Rika, Kiyonari Hiroshi, Ijiri Takashi, Taniguchi Kenichiro, Shawlot William, Hayashizaki Yoshihide, Westphal Heiner, Behringer Richard R, Matsuda Yoichi, Sakoda Saburo, Kondoh Hisato, Sasaki Hiroshi

Abstract excerpt

The transcriptional activity of LIM-homeodomain (LIM-HD) proteins is regulated by their interactions with various factors that bind to the LIM domain. We show that reduced expression of single-stranded DNA-binding protein 1 (Ssdp1), which encodes a co-factor of LIM domain interacting protein 1 (Ldb1), in the mouse mutant headshrinker (hsk) disrupts anterior head development by partially mimicking Lim1 mutants....

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PMID: 15857913
DOI: 10.1242/dev.01844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.PMID 15857913Read ↗

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