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Article

Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation

8 Feb 2008

Abstract excerpt

Bradykinin (BK) represents a pro-inflammatory mediator that partakes in many inflammatory diseases. The mechanism of action of BK is thought to be primarily mediated by specific cell surface membrane B2 receptors (B2Rs). Some evidence has suggested, however, the existence of an intracellular/nuclear B2R population. Whether these receptors are functional and contribute to BK signaling remains to be determined. In...

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PMID: 18264983
DOI: 10.1002/jcp.21398

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