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Article

Roles for interleukin-1β, phorbol ester and a post-transcriptional regulator in the control of bradykinin B1 receptor gene expression

15 Feb 1998

Abstract excerpt

Bradykinin B1 receptor (BKB1R) is involved in a variety of pathophysiological processes, particularly those related to inflammation. The gene for this receptor is known to be upregulated by interleukin (IL)-1beta, a proinflammatory cytokine. However, the molecular mechanisms involved in the regulation of the BKB1R gene expression have not been defined. We demonstrated that IL-1beta induces a rapid increase in...

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PMID: 9461531
DOI: 10.1042/bj3300361

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