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Article

Genetic and biological effects of sodium-chloride cotransporter (SLC12A3) in diabetic nephropathy.

American journal of nephrology - 1 Jan 2014

Abu Seman Norhashimah, He Bing, Ojala Juha R M, Wan Mohamud Wan Nazaimoon, Östenson Claes-Göran, Brismar Kerstin, Gu Harvest F

Abstract excerpt

BACKGROUND/AIMS: Solute carrier family 12 member 3 (SLC12A3) encodes a sodium/chloride transporter in kidneys. Previous reports suggest that Arg913Gln polymorphism in this gene is associated with diabetic nephropathy (DN), but the data appear to be inconsistent. Up to now, there is no biological evidence concerning the effects of SLC12A3 in DN. In this study, we aim to evaluate the genetic effects of the SLC12A3...

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PMID: 25401745
DOI: 10.1159/000368916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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