Article
Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice.
Development (Cambridge, England) - 1 Jan 2003
Kempermann Gerd, Gast Daniela, Kronenberg Golo, Yamaguchi Masahiro, Gage Fred H
Abstract excerpt
New neurons are continually generated in the adult hippocampus, but the important question, whether adult neurogenesis is transient or leads to the lasting presence of new neurons, has not yet been answered. Dividing cells were labeled with bromodeoxyuridine (BrdU) and were investigated by means of immunofluorescence and confocal microscopy at several time-points 1 day to 11 months thereafter. BrdU-labeled...
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