Article
The tumor suppressor, vitamin D3 up-regulated protein 1 (VDUP1), functions downstream of REPO during Drosophila gliogenesis.
Developmental biology - 15 Mar 2008
Mandalaywala Neil V, Chang Solomon, Snyder Randall G, Levendusky Mark C, Voigt Jeffrey M, Dearborn Richard E
Abstract excerpt
The tumor suppressor, vitamin D(3) up-regulated protein 1 (VDUP1), regulates cell cycle progression by suppressing AP-1-dependent transcription. Loss of VDUP1 activity is associated with tumorigenesis but little is known about VDUP1 regulatory controls or developmental roles. Here we show that the Drosophila homolog of human VDUP1 (dVDUP1) is expressed throughout the nervous system at all stages of development,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.