Article
Transcriptional regulation of the Drosophila glial gene repo.
Mechanisms of development - 1 Jun 2005
Lee Bruce P, Jones Bradley W
Abstract excerpt
reversed polarity (repo) is a putative target gene of glial cells missing (gcm), the primary regulator of glial cell fate in Drosophila. Transient expression of Gcm is followed by maintained expression of repo. Multiple Gcm binding sites are found in repo upstream DNA. However, while repo is expressed in Gcm positive glia, it is not expressed in Gcm positive hemocytes. These observations suggest factors in...
Topics
- Animals
- Binding Sites
- Cell Size
- Central Nervous System
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Epidermis
- Gene Expression Regulation, Developmental
- Genes, Insect
- Genes, Reporter
- Hemocytes
- Homeodomain Proteins
- Immunohistochemistry
- Lac Operon
- Models, Genetic
- Mutation
