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Article

Perturbation analysis: a simple method for filtering SNPs with erroneous genotyping in genome-wide association studies.

Annals of human genetics - 1 May 2008

Teo Y Y, Small K S, Clark T G, Kwiatkowski D P

Abstract excerpt

We introduce a simple and yet scientifically objective criterion for identifying SNPs with genotyping errors due to poor clustering. This yields a metric for assessing the stability of the assigned genotypes by evaluating the extent of discordance between the calls made with the unperturbed and perturbed intensities. The efficacy of the metric is evaluated by: (1) estimating the extent of over-dispersion of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18261185
DOI: 10.1111/j.1469-1809.2007.00422.x
PMCID: PMC2997476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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