Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down's syndrome.

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Article

Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down's syndrome.

Blood - 15 Mar 1991

Cossarizza A, Ortolani C, Forti E, Montagnani G, Paganelli R, Zannotti M, Marini M, Monti D, Franceschi C

Abstract excerpt

Peripheral blood lymphocyte subsets of two groups of patients affected by Down's syndrome (DS), ie, 28 children and nine adults of relatively advanced age (greater than 34 years), were investigated and compared with those of age- and sex-matched healthy controls (13 children and 20 adults). Particular attention was devoted to cells with markers of natural killer (NK) activity. Double- and triple-color...

Topics

Adolescent
Adult
Aging
Antigens, CD
Biomarkers
Child
Child, Preschool
Down Syndrome
Flow Cytometry
Fluorescent Antibody Technique
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon Type I

Interferon-gamma

Interleukin-2

Killer Cells, Natural

Lymphocyte Subsets

Lymphocytes

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 1825795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1825795-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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