Article
Upregulation of lymphocyte beta-adrenergic receptor in Down's syndrome: a biological marker of a neuroimmune deficit.
Journal of neuroimmunology - 1 Jun 1992
Morale M C, Batticane N, Cioni M, Marchetti B
Abstract excerpt
To test the hypothesis of an altered central nervous system influence upon the immune system of Down's syndrome (DS) patients and in order to establish a peripheral biological marker of neuroimmune deficit, we have studied the characteristics of the beta 2-adrenergic receptor (B2AR) system in per...
Topics
- Adolescent
- B-Lymphocytes
- Child
- Down Syndrome
- Female
- Humans
- Immune System
- Iodocyanopindolol
- Lymphocyte Subsets
- Lymphocytes
- Male
- Monocytes
- Nervous System
- Phenotype
- Pindolol
- Receptors, Adrenergic, beta
- Stereoisomerism
- T-Lymphocytes