Article
Immunology of Down syndrome: a review.
American journal of medical genetics. Supplement - 1 Jan 1990
Ugazio A G, Maccario R, Notarangelo L D, Burgio G R
Abstract excerpt
Subjects with Down syndrome (DS) have a high mortality due to infections and a high risk of developing malignancies. These observations, together with the demonstration of a frequent occurrence of HBsAg carrier state and of autoantibodies, have prompted investigations of the immune function in DS...
Topics
- Adolescent
- Adult
- Antibody Formation
- Autoantibodies
- B-Lymphocytes
- Child
- Child, Preschool
- Cytotoxicity, Immunologic
- Down Syndrome
- Humans
- Immunity, Cellular
- Infant
- Phagocytosis
- Phenotype
- T-Lymphocytes