Article
Age-related changes in natural killer cell receptors from childhood through old age.
Human immunology - 1 Apr 2011
Almeida-Oliveira Aline, Smith-Carvalho Monique, Porto Luis Cristovão, Cardoso-Oliveira Juliana, Ribeiro Aline dos Santos, Falcão Rosângela Rosa, Abdelhay Eliana, Bouzas Luis Fernando, Thuler Luiz Claudio Santos, Ornellas Maria Helena, Diamond Hilda Rachel
Abstract excerpt
Most studies on natural killer (NK) cells and aging have focused on overall cell numbers and global cytotoxic activity. NK cell functions are controlled by surface receptors belonging to three major families: killer cell immunoglobulin-like receptors (KIRs), natural cytotoxicity receptors (NCRs), and C-type lectins. The expression of these receptors was investigated from childhood through old age in T, NKT- and...
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